Maternal Deaths caused by COVID-19 Infection in the First Year of the Pandemic Wave

Authors

Muhammad Ilham Aldika Akbar, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Indonesian Society of Obstetricians and Gynecologists
Pungky Mulawardhana, Department of Obstetrics and Gynaecology, Rumah Sakit Universitas Airlangga, Surabaya, Indonesia; Indonesian Society of Obstetricians and Gynecologists
Manggala Pasca Wardhana, Department of Obstetrics and Gynaecology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia; Indonesian Society of Obstetricians and Gynecologists
Khanisyah Erza Gumilar, Department of Obstetrics and Gynaecology, Rumah Sakit Universitas Airlangga, Surabaya, Indonesia ; Indonesian Society of Obstetricians and Gynecologists
Ecccita Raheestyningtyas, Department of Obstetrics and Gynaecology, Rumah Sakit Universitas Airlangga, Surabaya, Indonesia; Indonesian Society of Obstetricians and Gynecologists
Muhammad Ardian Cahya Laksana, Department of Obstetrics and Gynaecology, Rumah Sakit Universitas Airlangga, Surabaya, Indonesia; Indonesian Society of Obstetricians and Gynecologists
Jimmy Yanuar Anas, Department of Obstetrics and Gynaecology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia ; Indonesian Society of Obstetricians and Gynecologists
Ernawati Syafa'ah, Department of Pulmonology and Respiratory Medicine, Dr. Soetomo Hospital, Surabaya, Indonesia
Hermanto Tri Joewono, Department of Obstetrics and Gynaecology, Rumah Sakit Universitas Airlangga, Surabaya, Indonesia ; Indonesian Society of Obstetricians and Gynecologists
Muhammad Adrianes Bachnas, Department of Obstetrics and Gynaecology, Faculty of Medicine, Dr. Moewardi General Hospital, Surakarta, Indonesia; Indonesian Society of Obstetricians and Gynecologists
Brahmana Askandar Tjokroprawiro, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Dr. Soetomo General Academic Hospital, Surabaya, Indonesia ; Indonesian Society of Obstetricians and Gynecologists

ORCID ID

Muhammad Ilham Aldika Akbar: https://orcid.org/0000-0002-2003-9282, Pungky Mulawardhana: https://orcid.org/0000-0001-7650-1053, Manggala Pasca Wardhana: https://orcid.org/0000-0001-8013-4639, Khanisyah Erza Gumilar: https://orcid.org/0000-0002-5050-2370, Muhammad Ardian Cahya Laksana: https://orcid.org/0000-0001-8585-5240, Jimmy Yanuar Anas: https://orcid.org/0000-0002-3589-4177, Ernawati: https://orcid.org/0000-0002-9344-3606, Hermanto Tri Joewono: https://orcid.org/0000-0003-4943-6369, Muhammad Adrianes Bachnas: https://orcid.org/0000-0002-1710-3909, Brahmana Askandar Tjokroprawiro: https://orcid.org/0000-0003-1658-3477

Abstract

Highlights: • These cases of maternal deaths caused by COVID-19 infections illustrated the significant risk factors for maternal mortality during the early phases of the pandemic, while studies had not extensively reported this. • COVID-19 infections increase the risk of maternal and neonatal mortality, with infants having a lower chance of survival even if they are delivered. • Respiratory support, antiviral medications, antibiotics, anticoagulants, and supportive care are the primary treatments for severe COVID-19 in pregnancy. Abstract This article presents seven cases of maternal deaths attributed to COVID-19 during the first year of the pandemic wave. These cases provide insights into the natural progression of COVID-19 in pregnant women who were not vaccinated. This study showed that COVID-19 significantly increased maternal and neonatal mortality and morbidity. All of the patients exhibited symptoms of fever, cough, and dyspnea upon admission to the hospital. They were admitted with elevated respiratory rates (26–32 times/minute) and low oxygen saturation (<95%). Four patients had obesity, while one patient had pregestational diabetes. The COVID-19 diagnosis was established using a rapid antibody or antigen test and chest X-ray, which indicated pneumonia. Medical interventions administered to the patients included antiviral therapy (5 patients), antibiotics (6 patients), and anticoagulants (4 patients). From a total of five babies delivered, four babies were delivered via cesarean section. Two babies were not delivered due to previability and maternal deaths before delivery. The patients passed away within 3–10 days of hospital admission. In conclusion, adequate and early intervention and management of pregnant women infected with COVID-19 are crucial in preventing maternal and neonatal deaths, especially in unvaccinated women.

First Page

187

Last Page

196

DOI

10.20473/fmi.v59i2.45226

Publication Date

6-10-2023

Recommended Citation

Akbar, Muhammad Ilham Aldika; Mulawardhana, Pungky; Wardhana, Manggala Pasca; Gumilar, Khanisyah Erza; Raheestyningtyas, Ecccita; Laksana, Muhammad Ardian Cahya; Anas, Jimmy Yanuar; Syafa'ah, Ernawati; Joewono, Hermanto Tri; Bachnas, Muhammad Adrianes; and Tjokroprawiro, Brahmana Askandar (2023) "Maternal Deaths caused by COVID-19 Infection in the First Year of the Pandemic Wave," Folia Medica Indonesiana: Vol. 59: No. 2, Article 3.
DOI: 10.20473/fmi.v59i2.45226
Available at: https://scholarly.unair.ac.id/fk-fmi/vol59/iss2/3