Review Article: Presepsin: New Biomaker to Evaluate Empirical Antibiotic Therapy Outcome in Septic Condition

Authors

Aldita Cahyani Puspitasari, Master Program of Clinical Pharmacy, Faculty of Pharmacy, Universitas Airlangga, Surabaya
Ayu Mawari, Master Program of Clinical Pharmacy, Faculty of Pharmacy, Universitas Airlangga, Surabaya
Joni Wahyuhadi, Department of Neurosurgery, Faculty of Medicine, Universitas Airlangga, Surabaya Neuroscience Institute, Dr. Soetomo Academic Medical Center Hospital, Surabaya
Eko Agus Subagio, Department of Neurosurgery, Faculty of Medicine, Universitas Airlangga, Surabaya Neuroscience Institute, Dr. Soetomo Academic Medical Center Hospital, Surabaya
Agus Turchan, Department of Neurosurgery, Faculty of Medicine, Universitas Airlangga, Surabaya Neuroscience Institute, Dr. Soetomo Academic Medical Center Hospital, Surabaya

Abstract

This review presents key publications from the research field of new biomarker of sepsis and other relevant journals during 2009-2015. The results of these experimental studies and clinical trials are discussed in the context of biomarker for sepsis and the accuracy of presepsin for optimising antibiotic therapy. The discussion highlights and summarises articles on three main topics: diagnostic and prognostic biomarkers, presepsin as new biomarkers, and outcome studies. According to the review, presepsin is specific biomarker for bacterial infections compare with CRP and PCT. It may be useful to evaluate the empirical antibiotic outcome in sepsis condition.

First Page

148

Last Page

153

DOI

10.20473/fmi.v56i2.21236

Publication Date

6-30-2020

Recommended Citation

Puspitasari, Aldita Cahyani; Mawari, Ayu; Wahyuhadi, Joni; Subagio, Eko Agus; and Turchan, Agus (2020) "Review Article: Presepsin: New Biomaker to Evaluate Empirical Antibiotic Therapy Outcome in Septic Condition," Folia Medica Indonesiana: Vol. 56: No. 2, Article 4.
DOI: 10.20473/fmi.v56i2.21236
Available at: https://scholarly.unair.ac.id/fk-fmi/vol56/iss2/4