Abstract
Acne vulgaris (AV) is an inflammation of pilosebaceous unit especially in young adult. The pathophysiology is the elevation of sebum production, keratinization of abnormal pilocebaseous follicles, and inflammation caused by immune response to Propionibacterium acnes. Therapy combination of oral antibiotics (doxycycline) and physical therapy (blue light) in moderate-severe acne is one option to reduce antibiotic resistance. Doxycycline is a commonly antibiotic used. The effects of photosensitive can increase the penetration of blue light by sebaceous glands. There was a total decrease in sebum and clinical improvement of combination therapy of blue light and doxycycline in seven patients. The combination therapy has been shown to improve its therapeutic effect, but more clinical trials are needed to prove the effectiveness of blue light with doxycycline than without blue light.
Keywords
Acne vulgaris, doxycycline, blue light
First Page
272
Last Page
275
DOI
10.20473/fmi.v53i4.7160
Publication Date
12-28-2017
Recommended Citation
Listiawan, M Yulianto; Prakoeswa, Cita Rosita Sigit; Handamari, Dhyah Aksarani; Indira, Regitta; and Yudiwati, Rina
(2017)
"Effects of blue light emitting diode (led) and doxycycline to sebaceous gland in acne vulgaris,"
Folia Medica Indonesiana: Vol. 53:
No.
4, Article 9.
DOI: 10.20473/fmi.v53i4.7160
Available at:
https://scholarly.unair.ac.id/fk-fmi/vol53/iss4/9
