Sub-acute stent thrombosis and in-stent restenosis associated with antiplatelets clopidogrel resistance and protein s deficiency

Authors

M Zakky Kurniawan
Iswanto Pratanu

Abstract

Protein S deficiency and antiplatelets clopidogrel resistance may uncommonly be responsible for coronary artery thrombosis. Hereby we report a patient presented with coronary disease, who had undergone PCI. However, two days later the patient was found in-stent thrombosis. Primary PCI was performed later with good result, but after 4 months evaluation with treadmill test we found significant ST depression in related region. It was suspected the patient had in-stent re-stenosis incidence. Further hematologic investigation showed that this patient had antiplatelets clopidogrel resistance and protein S deficiency. Double antiplatelet with another kind of antiplatelets and anticoagulant had given in this case. However, the remaining consideration is the choice for reperfusion strategy.

First Page

214

Last Page

220

DOI

10.20473/fmi.v51i4.2949

Publication Date

11-15-2016

Recommended Citation

Kurniawan, M Zakky and Pratanu, Iswanto (2016) "Sub-acute stent thrombosis and in-stent restenosis associated with antiplatelets clopidogrel resistance and protein s deficiency," Folia Medica Indonesiana: Vol. 51: No. 4, Article 1.
DOI: 10.20473/fmi.v51i4.2949
Available at: https://scholarly.unair.ac.id/fk-fmi/vol51/iss4/1